Gas Chromatography in the chemical and pharmaceutical industries.

Pharmaceutical Applications of Inverse Gas Chromatography

Inverse gas chromatography (IGC) represents a unique refinement of a classic chromatographic method has the potential to unlock some of the more difficult to measure physicochemical properties of pharmaceutical materials such as powder surface energies, acid/base/polar functionality of surfaces, diffusion kinetics, solubility parameters, surface heterogeneity and phase transition temperatures/h...

Objective colour assessment and quality control in the chemical, pharmaceutical and cosmetic industries

Impact of Pharmaceutical Impurities in Ecstasy Tablets: Gas Chromatography-Mass Spectrometry Study

In this study, a simple and reliable method by gas chromatograph–mass spectrometry (GC–MS) was developed for the fast and regular identification of 3, 4-MDMA impurities in ecstasy tablets. In so doing, 8 samples of impurities were extracted by diethyl ether under alkaline condition and then analyzed by GC–MS. The results revealed high MDMA levels ranging from 37.6% to 57.7%. The GC-MS method sh...

Impact of Pharmaceutical Impurities in Ecstasy Tablets: Gas Chromatography-Mass Spectrometry Study

In this study, a simple and reliable method by gas chromatograph–mass spectrometry (GC–MS) was developed for the fast and regular identification of 3, 4-MDMA impurities in ecstasy tablets. In so doing, 8 samples of impurities were extracted by diethyl ether under alkaline condition and then analyzed by GC–MS. The results revealed high MDMA levels ranging from 37.6% to 57.7%. The GC-MS method sh...

Consultants to the Pharmaceutical and Allied Industries

The petitioner requests that the Commissioner of the Food and Drug Administration declare that the drug product Divalproex Sodium Extended-Release Tablets, 1000 mg, is suitable for submissiol as an ANDA. The reference-listed drug product upon which this petition is based is Depakote ER (Divalproex Sodium) Extended-Release Tablets, 500 mg manufactured by Abbott Laboratories. The approval of whic...